Hi 4matt,
yes "How to read a paper" (Trisha Grishalm?), is about critically appraising a paper. It provides an approach, e.g. relevance of the paper, quality of the journal, credentials of the authors, inclusion and exclusion criteria, potential bias, will it change your practice etc. I think it is orientated on clinicians who need to assess literature and what impact this could have on their clinical practice.
I think the principles are OK, yet perhaps these are not specific enough for immunological studies.