Hello guys. I have a question for you. Currently I am looking for a postdoc and it seems I hit the wall. I would like to find a position where it is possible to change my focus to different methods that I've learned at my PhD, but PIs who look for postdocs prefer those who already know the methods they use (or would like to use). If you were a PI, would you take in a person who does not have all the preferred skills, but is willing to learn? The last thing I want is to fall into an overspecialization loop and become a specialist in one protein at the beginning of my career. What should I do to switch subfields/methods and thus, expand to become independent?

I think this is really going to depend on the PI. I know one person who got a postdoc where she has to use completely different techniques to those she used in her PhD but she was already known to the PI so I guess he knew she will be able to learn the new techniques and make fast progress.