I wold go for the friendly lab anyday! Some labs can have a really bad working environment and it will be a nightmare to do a PhD in them. Don't go for a project that you are not interested in at all - but if it is a choice of am amazing project in a horrible lab or an Ok project in a nice lab - go for the second one. You have to spend 3 years there... interest in the topic alone is not enough to get you through it....
We didn't answer this one because it's probably a matter of opinion.
A rule of thumb would be don't do a project which you have little interest in just because you like the people. Equally don't work with a bunch of Nazis just because one day you might get a paper in Nature.
muahahaha...i just got turned down for an amazing project in my home institution, with a really friendly supervisor, and great department. i think my institution is trying to get rid of me because i was unsuccessful for 3 different Phd schemes here. i have a first and a masters with distinction. annoyed and i would have preferred to stay here, but strangely have been accepted by cambridge now, to work in a horrible lab with some seriously good but serious postdocs. well, if it doesn't work out, then i will try and write up an Mphil, and reapply.
I worked as a research assistant in a lab in Oxford. The institute I was in had a great reputation and looked good on my CV but it was a nightmare working there because of the people. I felt so sorry for my friend who was doing a PhD there - she was misrable!
In my experience a PhD is a fairly solitary affair regardless of the size of your research group and mine is certainly no different from a job. Therefore it matters far more that you are interested enough in the subject matter to sit alone and think about it for years than what people in the lab/office might be like from 9-5.
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